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Excel · study · 2026

Transcriptome analysis of liver sinusoidal endothelial cells (LSECs) under palmitic acid treatment and IL-6/sIL-6R complex stimulation

Listed in NCBI GEO

This study investigates the transcriptional changes in liver sinusoidal endothelial cells (LSECs) following palmitic acid (PA) treatment and IL-6/sIL-6R complex stimulation.

Description

LSECs were cultured with PA for 12 hours and subsequently stimulated with the IL-6/sIL-6R complex for 1 hour to assess trans-signaling activation and gene expression changes. RNA sequencing was performed on four experimental groups: Control, PA, Complex, and PA+Complex.

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From keywords
Life Sciences
Inferred from text
RNA sequencing 75% · Sequencing 75%
Provenance · 1 source records, 9 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE30288412 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[modality].local:modality:rna-seqenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[modality].local:modality:sequencingenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[organism].NCBITaxon:9606source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title