Omics · study · 2026
Targeting Sufu-mediated Gli transcription alleviates ciliopathic phenotypes [Sufu_Null RNA-seq]
Listed in NCBI GEO
Suppressor of fused (Sufu) is a negative regulator of Hedgehog signaling.
Description
To define Sufu-dependent transcriptional programs during early craniofacial development, we performed polyA RNA-sequencing of microdissected embryonic day (E) 9.5 mouse heads from a Sufu null allele series: wild-type (Sufu+/+), Sufu null heterozygotes (Sufu null/+), and Sufu null homozygotes (Sufu null/null).
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE348nnn/GSE348431 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE348431 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1283947 ncbi.nlm.nih.gov/bioproject/PRJNA1283947 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Mus musculus
- From keywords
- Life Sciences
- Inferred from text
- RNA sequencing 65%
Provenance · 1 source records, 8 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE348431 | 12 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |