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Omics · study · 2026

SBNO1 knockdown in the iCCA cell lines SNU1079

Listed in NCBI GEO

Aberrant Notch signaling has been identified as a possible catalyst for hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA) development.

Description

Genetic studies in Drosophila observed that the knockout of strawberry notch (sno) mimics loss of notch. Here, we elucidated the role of the mammalian Strawberry Notch 1 (SBNO1) in HCC and CCA development.

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Life Sciences
Provenance · 1 source records, 7 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE27727114 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[organism].NCBITaxon:9606source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title