Short-Fiber Scaffold PGCL Stop Overgrowth for Endometrial Hyperplasia

Current treatments are hindered by the poor adaptability of rigid levonorgestrel (LNG)-releasing intrauterine systems. To overcome this, By physically loading LNG into the base PGC scaffold, we constructed a drug-loaded PGCL scaffold with improved therapeutic function.

To elucidate the underlying molecular mechanisms of PGCL scaffold therapy, we performed high-throughput RNA sequencing on Ishikawa cells treated with PGC and PGCL scaffolds, respectively.