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Omics · study · 2026

Effect of Intestinal Microbiome on Chromatin Accessibility in Paneth Cells

Listed in NCBI GEO

To assess epigenetic changes, ATAC-seq was performed on Paneth cells isolated from germ-free (GF) and specific pathogen-free (SPF) mice.

Description

The results revealed microbiome-dependent alterations in chromatin accessibility at key genomic loci involved in stemness regulation.

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From keywords
Life Sciences
Inferred from text
Genetics 69%
Provenance · 1 source records, 8 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE30295113 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].anzsrc:group:3105enrichment · NCBI GEOtaxonomy-embedding@1.1.0title+keywords+description (69%)
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:genome-binding-occupancy-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[organism].NCBITaxon:10090source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title