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Omics · study · 2026

Differential gene expression induced by doxorubicin in tumor-bearing and non–tumor-bearing mice

Listed in NCBI GEO

Doxorubicin-related cardiotoxicity is a major concern in cancer therapy and is influenced by drug dose, administration regimen, and host condition.

Description

While chemotherapy occurs under tumor-bearing conditions in clinical practice, most experimental studies evaluate cardiotoxicity in non–tumor-bearing models, which may alter cardiac responses to doxorubicin.

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Expression profiling by high throughput sequencing · Mus musculus
From keywords
Life Sciences
Inferred from text
Cancer 75% · Heart 65%
Provenance · 1 source records, 9 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE32451915 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[anatomy].local:anatomy:heartenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (65%)
concepts[disease].local:disease:cancerenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[organism].NCBITaxon:10090source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title