Table 1_From histological recovery to residual gastric cancer risk after Helicobacter pylori eradication: a multi-database bibliometric and clinical decision-domain analysis.xlsx

Temporal distributions were compared using Pearson's chi-square test, and a research-priority framework was synthesized by triangulating the quantitative findings with representative clinical evidence.</p>Results<p>Of 778 source records, 283 publications from 1993 to 2026 were included. Reviewer agreement was 78.80% (Cohen's kappa = 0.722). Histological regression and mucosal recovery predominated in 1993–2007 (34.7%), whereas surveillance and prevention (39.6%) and risk stratification (30.2%) became dominant in 2008–2017 and remained the leading domains in 2018–2026.

Domain distributions differed significantly across periods (P = 0.008) and remained significant after exclusion of the incomplete 2026 publication year. The principal translational gaps were the absence of externally validated multimodal risk thresholds and comparative evidence defining surveillance eligibility, intervals, duration, and outcomes.</p>Conclusion<p>The field has shifted from asking whether gastric mucosal damage can recover to determining who remains at risk and how that risk should be managed.

The resulting clinical decision taxonomy and research-priority framework support future validation of multimodal risk thresholds and comparative surveillance strategies; they do not establish universal surveillance or specific intervals.</p>