Excel · study · 2026
The high expression of siglec10 in tumor macrophages may promote the progression of colorectal cancer
Listed in NCBI GEO
SIGLEC10, also known as sialic-binding immunoglobulin-like lectin 10, is a member of the SIGLEC family.
Description
SIGLEC10 is expressed on the surface of immune cells and is involved in the regulation of immune responses by recognizing microorganisms or cells with specific sialic acids. Among other cancer types, SIGLEC10 has been identified as a novel tumor-associated macrophage-associated immune checkpoint.
This study suggests that siglec10 is an independent prognostic factor in patients with CRC and may be a promising immunotherapeutic target for CRC in the future.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE285nnn/GSE285319 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE285319 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1202511 ncbi.nlm.nih.gov/bioproject/PRJNA1202511 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Homo sapiens
- From keywords
- Life Sciences
- Inferred from text
- Cancer 75%
Provenance · 1 source records, 8 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE285319 | 13 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[disease].local:disease:cancer | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |