Omics · study · 2026
A single chromosome 3p break initiates clear cell renal cell carcinoma evolution
Listed in NCBI GEO
Bulk RNA sequencing was used to profile the transcriptomes of renal proximal tubule epithelial cells (RPTECs) harboring chromosome 3p loss.
Description
Three independent clones (Clone 5, Clone 7, and Clone 10) were sequenced at early (day 18) and late (day 90) passage alongside wild-type controls. Libraries were prepared from three independent biological replicates per condition and sequenced on an Illumina NovaSeq X Plus.
Differential gene expressions were assessed by comparing 3p-loss clones to wild-type RPTECs at each time point.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE336nnn/GSE336576 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE336576 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1482002 ncbi.nlm.nih.gov/bioproject/PRJNA1482002 ↗
project · from NCBI GEO
- PubMed 42465403 pubmed.ncbi.nlm.nih.gov/42465403 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Homo sapiens
- From keywords
- Life Sciences
- Inferred from text
- RNA sequencing 75% · Sequencing 75%
Related
- Possibly the same asA single chromosome 3p break initiates clear cell renal cell carcinoma evolution
Provenance · 1 source records, 9 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE336576 | 13 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[modality].local:modality:sequencing | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |