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Omics · study · 2026

Comparison of ER and PR genomic binding in T-47D

Listed in NCBI GEO

Genomic occupancy of estrogen receptor alpha (ER) and progesterone receptor (PR) was profiled by ChIP-seq in T-47D breast cancer cells.

Description

Occupancy was assessed for each receptor after treatment with endogenous ligand, estradiol (E2) for ER and progesterone (P4) for PR, or combination treatment of E2 and P4. Shifts in ER occupancy were observed between E2 and combination treatment that correspond to sites bound by PR.

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From keywords
Life Sciences
Inferred from text
Cancer 75%
Provenance · 1 source records, 8 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE34782914 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[disease].local:disease:cancerenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:genome-binding-occupancy-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[organism].NCBITaxon:9606source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title