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Omics · study · 2026

Integrated long- and short-read transcriptomics define TRP channel expression in adult mouse cortex

Listed in NCBI GEO

Transient receptor potential (TRP) ion channels are polymodal cation channels with well-established roles in peripheral sensory systems, whereas their expression landscape in the adult cerebral cortex remains incompletely defined.

Description

This study provides integrated Oxford Nanopore direct RNA sequencing and Illumina RNA-seq datasets from adult mouse cortex, together with Illumina RNA-seq of dorsal root ganglia as a peripheral sensory reference.

Three independent cortical biological replicates were profiled on both platforms. These datasets enable quantitative analysis of TRP channel gene- and isoform-level expression, cross-platform comparison of transcript abundance, and full-length transcript characterisation using long-read sequencing aligned to the Ensembl GRCm39 release 115 reference genome. Raw sequencing files and processed gene- and transcript-level expression tables are provided as a resource for transcriptomic analysis of adult mouse neural tissues.

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From keywords
Life Sciences
Inferred from text
RNA sequencing 75% · Sequencing 75%
Provenance · 1 source records, 9 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE31505114 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[modality].local:modality:rna-seqenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[modality].local:modality:sequencingenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[organism].NCBITaxon:10090source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title