Omics · study · 2026
ASK1-induces FGF21 expression in the liver
Listed in NCBI GEO
Increasing circulating fibroblast growth factor 21 (FGF21) concentrations may be an appealing strategy to prevent/treat obesity.
Description
Herein we identify apoptosis signal regulating kinase 1 (ASK1) as an inducer of hepatic FGF21 production. High fat diet (HFD)-fed liver-specific ASK1 overexpressing mice (ASK1+hep) revealed increased hepatic expression and circulating levels of FGF21.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE298nnn/GSE298858 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE298858 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1271512 ncbi.nlm.nih.gov/bioproject/PRJNA1271512 ↗
project · from NCBI GEO
- PubMed 42461584 pubmed.ncbi.nlm.nih.gov/42461584 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Mus musculus
- From keywords
- Life Sciences
Provenance · 1 source records, 7 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE298858 | 12 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |