Omics · study · 2026
Single Nuclei sequencing of mouse model of MBL1 and 2 KD
Listed in NCBI GEO
This study looks at a new model of MBL1 and MBL1 KD to understand how these proteins funciton in muscle development and contribute for DM1 pathology.
Description
Animals were injected into the tibialis anterior (TA) muscle at 10 weeks of age. Sampling was performed approximately 10 weeks after injection, i.e. at around 20 weeks of age.
The left TA was injected with an AAV encoding shmir directed against Mbnl1 and Mbnl2, and the left TA was injected with an AAV encoding shmir directed against LacZ (control). Both muscles were therefore injected with AAV.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE262nnn/GSE262646 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE262646 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1092697 ncbi.nlm.nih.gov/bioproject/PRJNA1092697 ↗
project · from NCBI GEO
- PubMed 42693134 pubmed.ncbi.nlm.nih.gov/42693134 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Mus musculus
- From keywords
- Life Sciences
- Inferred from text
- Sequencing 75%
Provenance · 1 source records, 8 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE262646 | 12 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:sequencing | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |