Excel · study · 2026
Bulk RNA sequencing of neutrophils and CD8 regulatory T cells in mouse models of ischemic stroke
Listed in NCBI GEO
Ischemic stroke induces profound alterations in peripheral immune responses, but the underlying molecular mechanisms remain incompletely understood.
Description
To characterize transcriptional changes in neutrophils and CD8 regulatory T cells (CD8 Tregs), we generated bulk RNA sequencing datasets from multiple in vivo and in vitro experimental settings. Bulk RNA sequencing was performed on peripheral blood neutrophils, purified CD8 Tregs, neutrophils harvested at different time points during in vitro culture, and neutrophils isolated following co-culture with CD8 Tregs.
These datasets provide a comprehensive resource for investigating transcriptional programs of neutrophils and CD8 Tregs associated with ischemic stroke.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE343nnn/GSE343620 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE343620 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1511991 ncbi.nlm.nih.gov/bioproject/PRJNA1511991 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Mus musculus
- From keywords
- Life Sciences
- Inferred from text
- RNA sequencing 75% · Sequencing 75%
Provenance · 1 source records, 9 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE343620 | 14 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[modality].local:modality:sequencing | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |