Omics · study · 2026
Epigenetic approaches by analysis of circulating miRNAs and global DNA methylation in veterinarians occupationally exposed to volatile anesthetics
Listed in NCBI GEO
Occupational exposure to waste anesthetic gases (WAGs) in veterinary operating rooms represents a potential health concern due to limited environmental monitoring.
Description
In this study, plasma samples from veterinarians chronically exposed to isoflurane and sevoflurane and from matched unexposed controls were analyzed to investigate molecular alterations associated with WAG exposure. Circulating microRNA expression was profiled using the NanoString nCounter® Human v3 miRNA Expression Assay.
Differential expression analysis was performed to identify miRNAs associated with occupational exposure. Additional bioinformatic analyses were conducted to explore the potential biological pathways related to the identified miRNAs.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE319nnn/GSE319599 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE319599 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1424707 ncbi.nlm.nih.gov/bioproject/PRJNA1424707 ↗
project · from NCBI GEO
- PubMed 41856424 pubmed.ncbi.nlm.nih.gov/41856424 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Homo sapiens · Non-coding RNA profiling by array
- From keywords
- Life Sciences
Provenance · 1 source records, 7 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE319599 | 14 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:non-coding-rna-profiling-by-array | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |