Omics · study · 2026
MicroRNA expression profiling of synovial fluid in early and late Osteoarthritis and comparison with Rheumatoid Arthritis
Listed in NCBI GEO
This study employed miRNA microarray profiling to characterize differential expression patterns in synovial fluid samples (n=14) obtained from patients with osteoarthritis across different disease stages, as well as from patients with rheumatoid arthritis.
Description
Comparative analyses were performed to explore variations in miRNA expression associated with disease progression and across related arthritic conditions. Selected miRNAs were further evaluated using quantitative real-time PCR (qRT-PCR) in an independent validation cohort comprising early-stage osteoarthritis, late-stage osteoarthritis, and rheumatoid arthritis patients.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE263nnn/GSE263015 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE263015 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1095455 ncbi.nlm.nih.gov/bioproject/PRJNA1095455 ↗
project · from NCBI GEO
- PubMed 41611143 pubmed.ncbi.nlm.nih.gov/41611143 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Homo sapiens · Non-coding RNA profiling by array
- From keywords
- Life Sciences
- Inferred from text
- Disease 75%
Provenance · 1 source records, 8 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE263015 | 13 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[disease].local:disease:disease | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:non-coding-rna-profiling-by-array | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |