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Omics · study · 2026

Mevalonate pathway-mediated regulation of double-negative regulatory T cell function protects against metabolic dysfunction-associated steototic liver disease

Listed in NCBI GEO

Double negative regulatory T cells (DNTreg) are important immune regulatory cells that maintain liver immune homeostasis and highly expressed enzymes of the mevalonate pathway.

Description

However, the role of the mevalonate pathway and the mechanism by which it modulates DNTregs in the pathogenesis of MASLD remain unknown.

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From keywords
Life Sciences
Inferred from text
Disease 75%
Provenance · 1 source records, 8 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE29556713 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[disease].local:disease:diseaseenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[organism].NCBITaxon:10090source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title