Omics · study · 2026
Temporal Transcriptomic Profiling Identifies Core Regulators in Cytokine-Induced Gut Barrier Disruption in Differentiated Caco-2 Cells
Listed in NCBI GEO
The intestinal epithelial barrier is a primary governor for gut homeostasis, and its disruption is a critical factor in the pathogenesis of many inflammatory diseases including Inflammatory Bowel Diseases (IBD).
Description
Although strategies to restore and enhance barrier function have been proposed as promising therapeutic approaches for treating inflammation-associated intestinal disorders, most therapies in development act on immune-cell response dampening rather than directly reinforcing epithelial function.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE314nnn/GSE314628 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE314628 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1392327 ncbi.nlm.nih.gov/bioproject/PRJNA1392327 ↗
project · from NCBI GEO
- PubMed 42257857 pubmed.ncbi.nlm.nih.gov/42257857 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Homo sapiens
- From keywords
- Life Sciences
Provenance · 1 source records, 7 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE314628 | 12 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |