Text · study · 2026
Mov10 suppresses excessive inflammation by regulating the TNFα–NF-KB pathway
Listed in NCBI GEO
We next sought to explore the underlying mechanism by which Mov10 regulates HSC function.We isolated Lin-c-kit+ cell from mice 12 days after 4.5 Gy IR and performed RNA immunoprecipi-tation sequencing (RIP-seq).
Description
Bioinformatics analysis identified Mov10-bound transcripts as po-tential Mov10 targets, with GO pathway enrichment analysis highlighting pathways related to production of molecular mediator of immune response and response to tumor necrosis factor (TNF)
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE305nnn/GSE305945 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE305945 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1308493 ncbi.nlm.nih.gov/bioproject/PRJNA1308493 ↗
project · from NCBI GEO
Topics
- Stated by source
- Mus musculus · Other
- From keywords
- Life Sciences
- Inferred from text
- Cancer 65% · Sequencing 75%
Provenance · 1 source records, 9 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE305945 | 14 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[disease].local:disease:cancer | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:other | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:sequencing | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |