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Text · study · 2026

Reconstituting central nervous system niche cues partially restores homeostatic identity in cultured murine primary microglia

Listed in NCBI GEO

Microglia rapidly lose their characteristic homeostatic phenotype after isolation and plastic adherence, undermining the interpretability of in vitro studies.

Description

We systematically evaluated culture conditions that reconstitute central nervous system (CNS) niche inputs to stabilize microglial identity.

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Life Sciences
Provenance · 1 source records, 7 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE31625214 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-arraysource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[organism].NCBITaxon:10090source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title