Data · dataset · 2022
Angiogenic, apoptotic and autophagic profiling of chronic myeloid leukaemia patients’ platelets ex vivo before and after treatment with Imatinib
Listed in UP Research Data Repository
<p>The data presented here was to determine the angiogenic, apoptotic, and autophagic profiles of chronic myeloid leukaemia patients <i>ex vivo</i> on platelets before and after treatment with Imatinib.
Description
Platelet counts, viability and activation were determined by human cluster of differentiation (CD) 41 and -62 markers. The possible occurrence of apoptosis and autophagy was measured by means of flow cytometry and western blot analysis via Annexin V-fluorescein isothiocyanate (FITC), caspase 3, autophagy related gene 5 (Atg5) and light chain I and II (LC3) markers.
Angiogenesis expression was determined through vascular endothelial growth factor (VEGF) and transforming growth factor β (TGFβ) markers.</p>
Links
Where it is published
- DOI doi.org/10.25403/upresearchdata.19145783.v1 ↗
DOI / persistent id · from researchdata up ac za
Catalogue records · 1
- OAI-PMH record api.figshare.com/v2/oai?verb=GetRecord&metadataPrefix=oai_dc&identifier=oai%3Af… ↗
metadata API · from researchdata up ac za
Topics
- From keywords
- Cancer cell biology · Earth & Environmental Science · Life Sciences · Medicine & Health
Provenance · 1 source records, 9 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| UP Research Data Repository | oai:figshare.com:article/19145783 | 17 h ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · researchdata up ac za | connector:researchdata_up_ac_za@1.0.0 | |
| concepts[field].anzsrc:field:321101 | mapping · researchdata up ac za | vocabulary-mapper@1.0.0 | keywords['Cancer cell biology'] |
| concepts[field].local:field:earth-environmental | mapping · researchdata up ac za | connector:researchdata_up_ac_za@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · researchdata up ac za | connector:researchdata_up_ac_za@1.0.0 | |
| concepts[field].local:field:medicine-health | mapping · researchdata up ac za | connector:researchdata_up_ac_za@1.0.0 | |
| description | source · researchdata up ac za | connector:researchdata_up_ac_za@1.0.0 | /metadata/dc/description |
| license | source · researchdata up ac za | connector:researchdata_up_ac_za@1.0.0 | /metadata/dc/rights |
| publication_date | source · researchdata up ac za | connector:researchdata_up_ac_za@1.0.0 | |
| title | source · researchdata up ac za | connector:researchdata_up_ac_za@1.0.0 | /metadata/dc/title |