31 datasets

figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Single-cell RNA sequencing

<p dir="ltr">Seurat object (Filtered, processed scRNA-seq data) from Sakimoto et al, BJC Reports, 2024 (https://doi.org/10.1038/s44276-024-00112-3).</p>

ZivaHub + Deakin Research Online + DMU Figshare + HKU DataHub + Swinburne Figshare + DaYta Ya Rona + SUNScholarData + figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Astronomical catalogue

<p dir="ltr">Stem cells and related research and therapy.</p><p dir="ltr"><br></p>

ZivaHub + Deakin Research Online + DMU Figshare + HKU DataHub + Swinburne Figshare + DaYta Ya Rona + SUNScholarData + figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Astronomical catalogue

<p dir="ltr">This dataset contains the raw data associated with Figure 5D of the manuscript.</p>

ZivaHub + HKU DataHub + DaYta Ya Rona + figshare + Loughborough Research Repository + UP Research Data Repository2026 · RNA sequencing

<p dir="ltr"><a href="https://figshare.com/account/articles/30597953" target="_blank">Differentially expressed genes in response to BN-treatment</a></p>

ZivaHub2026 · dataset

<p dir="ltr">Glioblastoma (GBM) is characterized by profound metabolic heterogeneity and plasticity, enabling tumor-cell populations to adapt to energetic, oxidative, and therapeutic stress. Dual Fuel Modulation (DFM) is proposed as a hypothesis-generating metabolic framework designed to investigate whether this adaptive capacity can be converted into a therapeutic vulnerability through coordinate

HKU DataHub + figshare + Loughborough Research Repository + UP Research Data Repository2026 · Astronomical catalogue

Purpose<p>The incidence of end-stage renal disease (ESRD) caused by renal cell carcinoma (RCC) is increasing with the high prevalence of RCC as well as those with treatment-related renal function impairment. Worries about tumor recurrence after transplant-related immunosuppression hinder the recommendation of kidney transplantation for RCC-induced ESRD patients. However, no direct analysis has bee

HKU DataHub + figshare + Loughborough Research Repository + UP Research Data Repository2026 · Astronomical catalogue

Purpose<p>The incidence of end-stage renal disease (ESRD) caused by renal cell carcinoma (RCC) is increasing with the high prevalence of RCC as well as those with treatment-related renal function impairment. Worries about tumor recurrence after transplant-related immunosuppression hinder the recommendation of kidney transplantation for RCC-induced ESRD patients. However, no direct analysis has bee

ZivaHub2026 · dataset

<p dir="ltr">This protocol outlines an in vitro experimental strategy for validating Dual Fuel Modulation (DFM) in glioblastoma (GBM) models while simultaneously evaluating candidate adaptive resistance pathways. The study combines coordinated metabolic perturbation—glycolytic inhibition, System Xc⁻ blockade, polyunsaturated fatty acid enrichment, and partial mitochondrial modulation—with mechanis

ZivaHub2026 · dataset

<p><br></p><p dir="ltr">Dual Fuel Modulation (DFM) proposes that coordinated metabolic pressure may increase ferroptotic vulnerability in selected glioblastoma (GBM) phenotypes. However, an important unanswered question is how surviving tumor cells adapt to this stress and restore metabolic and redox homeostasis. This companion hypothesis proposes that DFM-induced metabolic stress may activate lay

figshare + Loughborough Research Repository2026 · Astronomical catalogue

<p>Cancer-associated cadherin 20 (CDH20) is a novel identified cadherin that is genetically altered in several types of human cancer, including cervical cancer. However, its involvement in the progression of cervical cancer remains unknown. In this study, we show that CDH20 was downregulated in clinical cervical cancer samples and its expression correlated with cervical cancer clinical features. C

figshare + Loughborough Research Repository2026 · Astronomical catalogue

Cancer Organoid Data

figshare + Loughborough Research Repository2026 · Astronomical catalogue

<p dir="ltr">Data was generated by staining established cell lines and patient samples with a custom antibody panel (PLURIpanel), using CyTOF (mass cytometry) to profile stem cell marker expression.</p><p dir="ltr">hPSCs.fcs H7 (WiCell Research Institute, Madison, WI)</p><p dir="ltr">hPSCs BMP4 72h.fcs H7 (WiCell Research Institute, Madison, WI), BMP-4 (R&D, CF 314-BP-010) treatment was applied at

figshare + Loughborough Research Repository2026 · Astronomical catalogue

<p dir="ltr">The combined dataset contains results (both raw and processed data) from experiments performed for the study 'Role of Triacylglycerol Synthesis and Utilization in Hepatocellular Carcinoma'.</p><p dir="ltr">The data are organized in files according to the assays performed, including Flow cytometry, <i>in vivo </i>orthotopic injection and hydrodynamic tail vein injection, metabolomics a

figshare + Loughborough Research Repository2026 · Astronomical catalogue · restricted

<p dir="ltr">This dataset contains research data supporting Chapter 3 of the PhD thesis “CENPA suppression for epigenetic correction in hepatocellular carcinoma.” It is organized into 34 folders corresponding to individual thesis figures (Figures 3.2.1–3.8).</p><p dir="ltr">The dataset includes de-identified clinical and clinicopathological data from a hepatocellular carcinoma cohort; analyses of

figshare + Loughborough Research Repository2026 · Astronomical catalogue

Background<p>The survival for many children with relapsed/refractory cancers remains poor despite advances in therapies. Arginine metabolism plays a key role in the pathophysiology of a number of pediatric cancers. We report the first in child study of a recombinant human arginase, BCT-100, in children with relapsed/refractory hematological, solid or CNS cancers.</p>Procedure<p>PARC was a single a

figshare + Loughborough Research Repository2026 · Astronomical catalogue

<p dir="ltr">Raw data for nuclear morphology analysis workflow of neuroblastoma cell lines</p>

figshare + Loughborough Research Repository2026 · Astronomical catalogue · restricted

<p dir="ltr">This dataset accompanies a study characterising the immune microenvironment of IDH1-mutant intrahepatic cholangiocarcinoma (iCCA). By investigating the impact of the oncometabolite R-2HG on primary murine cells, novel immunotherapeutic strategies for IDH1-mutant iCCA were identified. The repository contains quantitative IDH1 expression data from engineered murine iCCA cell lines, alon

figshare + Loughborough Research Repository2026 · Astronomical catalogue

<p dir="ltr">This dataset was generated as part of a research project investigating how transfer RNA (tRNA) abundance and tRNA modification regulate codon-dependent translation in hepatocellular carcinoma (HCC). The data cover two complementary aspects of tRNA-mediated translational regulation.</p><p dir="ltr">The first project examines the relationship between transcriptome-derived codon demand a

figshare + Loughborough Research Repository2026 · Astronomical catalogue

<p dir="ltr">This study explores the underlying mechanism by which mitochondrial translation supports therapeutic resistance to ivosidenib, which is the targeted therapy for IDH1-mutated intrahepatic cholangiocarcinoma. Using a genome-wide CRISPR library screen in iCCA cells, we identified MTFMT and MTRF1L, mitochondrial translation regulators, as key resistance mechanisms. MTFMT and MTRF1L knockd

figshare + Loughborough Research Repository2026 · Astronomical catalogue

Cancer Organoid Data<p></p>

figshare2026 · Astronomical catalogue

Background<p>The clinical role of deficient DNA mismatch repair (dMMR)/microsatellite instability-high (MSI-H) in gastric cancer (GC) is still controversial. We aimed to analyze the relationship between dMMR/MSI-H and clinicopathological features along with survival.</p>Methods<p>Patients who were diagnosed with GC at the three big cancer centers in China from 2015 to 2020 were evaluated retrospec

figshare2026 · Astronomical catalogue

<p dir="ltr">Revised source data for the manuscript "Nanoparticle retention in solid tumours"</p>

figshare2026 · Astronomical catalogue

<p dir="ltr">Revised source data for the manuscript "Nanoparticle retention in solid tumours" Supplementary Information</p>

figshare2026 · Astronomical catalogue

Background<p>The clinical role of deficient DNA mismatch repair (dMMR)/microsatellite instability-high (MSI-H) in gastric cancer (GC) is still controversial. We aimed to analyze the relationship between dMMR/MSI-H and clinicopathological features along with survival.</p>Methods<p>Patients who were diagnosed with GC at the three big cancer centers in China from 2015 to 2020 were evaluated retrospec

figshare2026 · Astronomical catalogue

This Excel file contains the source data underlying all graphs presented in the manuscript. Data are organized by figure and panel, with each worksheet corresponding to an individual figure. The file includes the values used to generate the figures and perform the statistical analyses.