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Omics · study · 2026

Comparative DNA methylation profiling of highly invasive and parental patient-derived glioblastoma stem-like cells using the Illumina Infinium MethylationEPIC array

Listed in NCBI GEO

This dataset contains genome-wide DNA methylation profiles of patient-derived glioblastoma stem-like cells (GSCs) generated using the Illumina Infinium MethylationEPIC BeadChip array.

Description

A highly invasive subpopulation was established by serial transwell invasion selection and compared with the parental, non-selected population. The dataset was generated to identify DNA methylation changes associated with a stable invasive phenotype in glioblastoma cells and to enable analysis of regulatory regions and transcription factor motif-associated methylation patterns linked to invasion.

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From keywords
Life Sciences
Inferred from text
DNA methylation profiling 75%
Provenance · 1 source records, 8 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE3246648 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:methylation-profiling-by-genome-tiling-arraysource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[method].local:method:dna-methylation-profilingenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[organism].NCBITaxon:9606source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title