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Omics · study · 2026

Maternal obesity Reprograms Offspring Intestinal Epithelium via Tuft Cell-Mediated ECM-Integrin Signaling

Listed in NCBI GEO

We established a maternal obesity rat model using a high-fat diet. scRNA-seq was performed on E19.5 fetal colon.

Description

CellChat and hdWGCNA were used to analyze intercellular communication and identify functional modules. Inflammatory cytokines were detected by the Luminex Assay.

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Life Sciences
Inferred from text
Single-cell RNA sequencing 65%
Provenance · 1 source records, 8 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE31997612 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[modality].local:modality:single-cell-rna-seqenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (65%)
concepts[organism].NCBITaxon:10116source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title