Data · study · 2026
Expression data from Txnrd2 deficient mouse gastrocnemius muscle
Listed in NCBI GEO
TXNRD2, encoded by Txnrd2, is a mitochondrial enzyme of the pyridine nucleotide–disulfide oxidoreductase family and a key component of the thioredoxin system, essential for maintaining redox homeostasis.
Description
Because skeletal muscle is highly metabolically active and depends on efficient mitochondrial function and redox balance to sustain energy production, we aimed to investigate the role of Txnrd2 in skeletal muscle. The Clariom S Mouse microarray from Affymetrix was used to investigate the dysregulation of gene expression in the gastrocnemius muscle of mice with a muscle-specific deletion of Txnrd2.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE310nnn/GSE310521 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE310521 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1366462 ncbi.nlm.nih.gov/bioproject/PRJNA1366462 ↗
project · from NCBI GEO
- PubMed 41996932 pubmed.ncbi.nlm.nih.gov/41996932 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by array · Mus musculus
- From keywords
- Life Sciences
Provenance · 1 source records, 7 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE310521 | 14 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-array | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |