scRNAseq of human intestinal organoids infected with coxsackievirus B1

The intestinal epithelium represents the first line of defense in the gastrointestinal tract, forming an essential barrier that, when compromised, renders individuals with celiac disease (CeD) susceptible to mucosal damage. By connecting viral infections and gluten challenges, this study sheds light on a mechanistic bridge between viral infection and gluten peptide modification, a critical step in the onset of CeD.