Array · study · 2026
Spatial transcriptomics for intrathoracic adhesion in mice
Listed in NCBI GEO
Intrathoracic adhesions (IAs) complicate thoracic surgery, causing risks such as bleeding, prolonged operative time, and postoperative air leakage.
Description
Severe adhesions (>10% pleura) often necessitate conversion from VATS to open thoracotomy due to dissection difficulties and pleural damage. Given the increasing role of lung segmentectomy and re-lobectomy for small or recurrent NSCLC, reoperations with IA are expected to rise, highlighting the need for effective IA prevention.
This study aimed to establish such a murine IA model, evaluate pathological and gene expression changes, and identify targets to prevent lung–chest wall adhesions.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE308nnn/GSE308260 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE308260 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1329320 ncbi.nlm.nih.gov/bioproject/PRJNA1329320 ↗
project · from NCBI GEO
- PubMed 42230567 pubmed.ncbi.nlm.nih.gov/42230567 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Mus musculus · Other
- From keywords
- Life Sciences
Provenance · 1 source records, 7 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE308260 | 14 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:other | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |