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Excel · study · 2026

Developing a pan cancer therapy based on DISE inducing short RNAs [DISE-069.RNAseq]

Listed in NCBI GEO

Developing two different DISE inducing sRNAs.

Description

The first is based on the 6mer seed GGGGGC (G5C) and the second on CAG trinucleotide repeat sequences.This RNA seq analysis was designed to identify the most deregulated genes in ID8p53-/-Brca2-/- (DKO) cells transfected with either of the two Di-sRNAs, each compared to the nontargeting control sNT8.

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Stated by source
Expression profiling by high throughput sequencing · Mus musculus
From keywords
Life Sciences
Inferred from text
Cancer 75% · RNA sequencing 65%
Provenance · 1 source records, 9 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE31233414 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[disease].local:disease:cancerenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[modality].local:modality:rna-seqenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (65%)
concepts[organism].NCBITaxon:10090source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title