Omics · study · 2026
CUT&RUN profiling of SOX11 and SMARCA4 in mantle cell lymphoma
Listed in NCBI GEO
CUT&RUN experiments were performed in mantle cell lymphoma (MCL) cell lines (Z138, Granta-519, and JVM2) under different genetic and treatment conditions.
Description
In Z138 cells (wild-type and SOX11 knockout), samples were either untreated or treated with the PROTAC degrader AU-15530 0.5 µM for 24 hours. In JVM2 cells, three conditions were tested: parental JVM2, JVM2TRE-SOX11:HA, and JVM2TRE-SOX11:HA treated with AU-15530 0.5 µM for 24 hours.
Antibodies against SOX11, SMARCA4, and IgG (as negative control) were used. Peaks were called and visualized using BigWig signal tracks, which are provided as supplementary processed data.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE302nnn/GSE302906 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE302906 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1292801 ncbi.nlm.nih.gov/bioproject/PRJNA1292801 ↗
project · from NCBI GEO
- PubMed 40739087 pubmed.ncbi.nlm.nih.gov/40739087 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Genome binding/occupancy profiling by high throughput sequencing · Homo sapiens
- From keywords
- Life Sciences
Provenance · 1 source records, 7 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE302906 | 12 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:genome-binding-occupancy-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |