Data · study · 2026
TGF-alpha/EGFR signalling mediates retinoic acid-induced lung repair
Listed in NCBI GEO
Retinoic acid (RA) signalling is an important regulator of lung development and repair.
Description
To investigate the molecular mechanisms underlying RA-mediated responses in lung endothelial cells, we profiled the gene expression of human pulmonary microvascular endothelial cells (HPMECs) treated with RA or ethanol (EtOH) vehicle control. Whole-genome expression analysis using Affymetrix Human U133 Plus 2.0 GeneChips identified transcriptional changes associated with angiogenesis, wound healing, and signalling pathways relevant to alveolar repair.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE307nnn/GSE307491 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE307491 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1321876 ncbi.nlm.nih.gov/bioproject/PRJNA1321876 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by array · Homo sapiens
- From keywords
- Life Sciences
Provenance · 1 source records, 7 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE307491 | 13 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-array | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |