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Omics · study · 2026

Elucidating the impact of chemotherapy on skeletal progenitors [bulk ATAC-seq]

Listed in NCBI GEO

Mice receiving cyclic doxorubicin (DOX) treatment exhibited long-term skeletal defects.

Description

Lineage tracing experiments revealed loss of osteogenesis from bone marrow mesenchymal stem and progenitor cells. We performed molecular characterization on MSPCs to understand the mechanisms underying MSPC dysfunction folloiwng DOX treatment.

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From keywords
Life Sciences
Provenance · 1 source records, 7 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE29675912 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:genome-binding-occupancy-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[organism].NCBITaxon:10090source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title