Excel · study · 2026
KAT7-Driven Lactylation of CCAR2 Promotes Macrophage Extracellular Traps Formation and Accelerates Atherosclerosis Progression
Listed in NCBI GEO
KAT7 regulates macrophage foam cell formation and atherosclerosis progression.
Description
To identify transcriptional changes associated with KAT7 deficiency in macrophages, bulk RNA-seq was performed using bone marrow-derived macrophages (BMDMs) from Ctrl and KAT7KO mice. Three biological replicates were included for each group.
Differential expression analysis was performed for KAT7KO versus Ctrl to identify KAT7-regulated genes and pathways in macrophages.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE338nnn/GSE338728 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE338728 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1495775 ncbi.nlm.nih.gov/bioproject/PRJNA1495775 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Mus musculus
- From keywords
- Life Sciences
- Inferred from text
- RNA sequencing 65%
Provenance · 1 source records, 8 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE338728 | 12 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |