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Omics · study · 2026

Bulk B Cell Receptor Sequencing of mouse ileum; paired sample with MERFISH imaging

Listed in NCBI GEO

Plasma B cell clones each express a single B cell receptor that has high binding specificity to a narrow set of antigens.

Description

New spatial technologies have been introduced that aim to capture the clonality of plasma cell populations in situ. BCR-MERFISH is an imaging- and probe-based spatial approach that targets the V genes of heavy and light chains that comprise B cell receptors within single cells.

To assess how accurately BCR-MERFISH reports V gene usage, this BCR-sequencing dataset was collected from paired samples that were imaged with BCR-MERFISH.

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From keywords
Life Sciences
Inferred from text
Imaging 75% · Sequencing 75%
Provenance · 1 source records, 10 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE29598913 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[method].geo_series_type:othersource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[modality].local:modality:imagingenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[modality].local:modality:sequencingenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[organism].NCBITaxon:10090source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title