Omics · study · 2026
Effects of PAK4 deficiency on the transcriptome of hepatic stellate cells
Listed in NCBI GEO
Hepatic stellate cell (HSC) activation plays a pivotal role in the progression of liver fibrosis.
Description
We investigated how the loss of p21-activated kinase 4 (PAK4), an emerging therapeutic target, influences key features of HSCs. To elucidate the underlying molecular mechanisms, we carried out RNA-sequencing using PAK4-deficient HSCs.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE308nnn/GSE308719 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE308719 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1332601 ncbi.nlm.nih.gov/bioproject/PRJNA1332601 ↗
project · from NCBI GEO
- PubMed 42527392 pubmed.ncbi.nlm.nih.gov/42527392 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Mus musculus
- From keywords
- Life Sciences
Provenance · 1 source records, 7 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE308719 | 13 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |