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Omics · study · 2026

Role of mitochondrial RNase P complex in the processing of primary RNA in human mitochondria

Listed in NCBI GEO

The human mitochondrial genome is transcribed into long polycistronic RNA that undergoes subsequent endonucleolytic processing.

Description

The role of the mitochondrial RNase P, a protein complex composed of RNA methyltransferase, ribonuclease and dehydrogenase, has been revealed in the processing of the primary mitochondrial RNA. Still, the contribution of catalytic activities of RNase P subunits in the processing of individual processing sites has not been fully described.

This study aims to define the role of RNase P subunits in regulating the efficiency of the processing of the primary mitochondrial RNA.

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From keywords
Life Sciences
Provenance · 1 source records, 7 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE23589014 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[organism].NCBITaxon:9606source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title