Omics · study · 2026
Gene Expression Profiling in Diffuse Large B-Cell Lymphoma (DLBCL) Cell Lines Treated with Selinexor
Listed in NCBI GEO
This study focuses on the transcriptional response of diffuse large B-cell lymphoma (DLBCL) cell lines, SU-DHL6 and OCI-LY3, to Selinexor treatment.
Description
Selinexor, a selective inhibitor of nuclear export (SINE), is known for its antitumor properties. RNA-sequencing was performed to investigate gene expression changes in these DLBCL models after 24 and 48 hours of treatment.
The goal is to uncover key molecular pathways and targets influenced by Selinexor, providing insights into its therapeutic potential in DLBCL.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE283nnn/GSE283388 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE283388 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1193560 ncbi.nlm.nih.gov/bioproject/PRJNA1193560 ↗
project · from NCBI GEO
- PubMed 41857699 pubmed.ncbi.nlm.nih.gov/41857699 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Homo sapiens
- From keywords
- Life Sciences
Provenance · 1 source records, 7 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE283388 | 14 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |