Omics · study · 2026
Effect of pancreatic tumor interstitial fluid media on transcriptional responses in PDAC cells
Listed in NCBI GEO
Local metabolic signals can influence the transcriptional response.
Description
To better understand the effect of the microenvironment in pancreatic adenocarcinoma (PDAC), we compared pancreatic tumor interstitial fluid media (TIFM - described by Muir et al., eLife 2023) to regular media in two PDAC cell lines, MiaPaCa and Panc1, under two conditions, normoxia and hypoxia.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE319nnn/GSE319951 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE319951 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1425608 ncbi.nlm.nih.gov/bioproject/PRJNA1425608 ↗
project · from NCBI GEO
- PubMed 41932308 pubmed.ncbi.nlm.nih.gov/41932308 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Homo sapiens
- From keywords
- Life Sciences
- Inferred from text
- Cancer 65%
Provenance · 1 source records, 8 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE319951 | 14 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[disease].local:disease:cancer | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |