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Data · study · 2026

A global transcriptome analysis of human dermal fibroblasts upon knockdown of the circular RNAs CircMT-RNR2

Listed in NCBI GEO

In an RNAseq analysis, we have identified CircMT-RNR2 with lower levels in diabetic foot ulcer compared to healthy skin The biological function of CircMT-RNR2 in human dermal fibroblasts during wound repair has not been studied.

Description

To study the genes regulated by CircMT-RNR2, we transfected siRNA into human dermal fibroblasts to knockdown CircMT-RNR2. We performed a global transcriptome analysis of fibroblasts upon circRNA knockdown using Affymetrix arrays.

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Life Sciences
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RNA sequencing 65%
Provenance · 1 source records, 8 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE30163615 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-arraysource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[modality].local:modality:rna-seqenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (65%)
concepts[organism].NCBITaxon:9606source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title