Omics · study · 2026
RNA-seq of mouse tissue samples from animal model : Effects of AREG on gene expression
Listed in NCBI GEO
In the present study, RNA-seq technique were performed to explore biological significance of AREG in the neuro-cutaneous signaling network of chronic itch.
Description
At least f repetitive mRNAs were deeply sequenced using MGISEQ-2000 to generate an mRNA profiles. In high-throughput sequencing of tissue samples using protein and control solvent intradermal injection, we found that increased intradermal AREG affected the expression of multiple pruritus and skin inflammatory factors associated with human chronic dermatitis dermatitis dermatitis dermatitis dermatitis dermatitis dermatitis.
These changes may indicate that AREG is closely related to inflammation and pruritus. This finding might help us to better understand the immune-neuro-modulatory mechanism in itch circuits.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE232nnn/GSE232421 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE232421 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA971961 ncbi.nlm.nih.gov/bioproject/PRJNA971961 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Mus musculus
- From keywords
- Life Sciences
- Inferred from text
- RNA sequencing 65% · Sequencing 75%
Provenance · 1 source records, 9 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE232421 | 12 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[modality].local:modality:sequencing | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |