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Omics · study · 2026

Positive and Negative Selection of abT cells (OT-I and OT-II) in the thymus 1 -scRNA-seq, CITE-seq and TCRab [I58]

Listed in NCBI GEO

This study is part of the immgenT Open Source Project, specifically from IGT58, focuses on the positive and negative selection of OT1 and OT2 in the thymus.

Description

Bone marrow chimeras were generated by transplanting OT1 or OT2 CD45.1.2 and wild-type competitor BM into wild-type, RIPmOVA, B2m -/- or MHCII -/- hosts. From those mice, OT1 and OT2, not selected, positively selected, or negatively selected, were profiled.

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From keywords
Life Sciences
Provenance · 1 source records, 8 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE33089613 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[method].geo_series_type:othersource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[organism].NCBITaxon:10090source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title