Omics · study · 2026
Single cell RNAseq analysis in CT27 human TSC with and without PRMT1 Knockdown
Listed in NCBI GEO
The study reports single cell RNA seq analyses of gene expression dynamics in human TSCs.
Description
Protein Arginine Methyl Transferase 1 (PRMT1) regulates cellular function via methylation of arginine residues on its target proteins. In this study we depleted PRMT1 in CT27 human TSCs via RNAi.
Loss of PRMT1 affects human TSC self-renewal process. We performed single cell RNA-seq with control and PRMT1-knocked down CT27 human TSCs to capture gene expression dynamics at a single cell resolution.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE295nnn/GSE295665 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE295665 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1255558 ncbi.nlm.nih.gov/bioproject/PRJNA1255558 ↗
project · from NCBI GEO
- PubMed 42431891 pubmed.ncbi.nlm.nih.gov/42431891 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Homo sapiens
- From keywords
- Life Sciences
- Inferred from text
- RNA sequencing 65%
Provenance · 1 source records, 8 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE295665 | 14 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |