Omics · study · 2026
RNA-seq of bone marrow-derived macrophages(BMDMs) coclutured with mEC25 cancer cell lines
Listed in NCBI GEO
Description
Our findings revealed that when BMDMs cocultured with cancer cell lines in contact, auch as mEC25,their SIRPαexpression would upregulated compared with their coculture in a non-contact manner.To investigate the underlying mechanism and the altered signaling pathway involved in the SIRPα upregulation in BMDMs when their co-culture with cancer cell lines.We conduct RNA-seq based on sorting BMDMs after their co-culture with cancer cell lines in a direct or indirect way.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE274nnn/GSE274929 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE274929 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1148492 ncbi.nlm.nih.gov/bioproject/PRJNA1148492 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Mus musculus
- From keywords
- Life Sciences
- Inferred from text
- Cancer 75% · RNA sequencing 65%
Provenance · 1 source records, 9 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE274929 | 12 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[disease].local:disease:cancer | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |