Omics · study · 2026
Assessing the impact of microplastics in inflammatory liver conditions using spatial single cell transcriptomics
Listed in NCBI GEO
Recent evidence highlights the multisystem effects of microplastics.
Description
We investigated the effect of the most common microplastic, polyethylene, on liver conditions. We included 4 experimental groups of mice; chow diet, chow diet and microplastics, high-fat/fructose/cholesterol diet, high-fat/fructose/cholesterol diet and microplastics.
Following tissue collection after treatment, bulk RNA sequencing was carried out to profile transcriptomic activity of each group.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE294nnn/GSE294180 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE294180 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1248512 ncbi.nlm.nih.gov/bioproject/PRJNA1248512 ↗
project · from NCBI GEO
- PubMed 42308314 pubmed.ncbi.nlm.nih.gov/42308314 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Mus musculus
- From keywords
- Life Sciences
- Inferred from text
- RNA sequencing 75% · Sequencing 75%
Provenance · 1 source records, 9 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE294180 | 12 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[modality].local:modality:sequencing | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |