Omics · study · 2026
Single cell RNA-seq analysis of PBMCs from mouse models of mevalonate kinase deficiency
Listed in NCBI GEO
The single cell RNA sequencing data here were used in the publication "NK cell dysfunction and interferon gamma production underlie autoinflammation in mevalonate kinase deficiency".
Description
This study sought to identify changes in immune cell populations in peripheral blood of MvkV377I/del91 mutant mice (a genetic model of mevalonate kinase deficiency described in; Munoz et al. 2022, J Clin Invest 132(19):e160929. doi: 10.1172/JCI160929).
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE298nnn/GSE298361 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE298361 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1269014 ncbi.nlm.nih.gov/bioproject/PRJNA1269014 ↗
project · from NCBI GEO
- PubMed 42066777 pubmed.ncbi.nlm.nih.gov/42066777 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Mus musculus
- From keywords
- Life Sciences
- Inferred from text
- RNA sequencing 75% · Sequencing 75%
Provenance · 1 source records, 9 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE298361 | 13 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[modality].local:modality:sequencing | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |