Excel · study · 2026
RNA-seq of liver, kidney, and quadriceps muscle from corylin-treated and control C57BL/6J mice
Listed in NCBI GEO
To elucidate the transcriptional mechanisms underlying longevity and sex-specific responses to pharmacological intervention, we performed RNA sequencing on liver, kidney, and quadriceps muscle tissues from male and female C57BL/6J mice subjected to long-term dietary administration of corylin or standard diet.
Description
Total RNA was extracted using TRIzol, and libraries were prepared with the TruSeq Stranded mRNA protocol. Sequencing was conducted on the Illumina NovaSeq platform to generate 150 bp paired-end reads.
This dataset constitutes a tissue- and sex-resolved transcriptomic resource for delineating corylin-regulated molecular programs and supports integrative multi-omic analyses targeting age-associated pathways.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE305nnn/GSE305103 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE305103 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1302561 ncbi.nlm.nih.gov/bioproject/PRJNA1302561 ↗
project · from NCBI GEO
- PubMed 42265126 pubmed.ncbi.nlm.nih.gov/42265126 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Mus musculus
- From keywords
- Life Sciences
- Inferred from text
- RNA sequencing 75% · Sequencing 75%
Provenance · 1 source records, 9 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE305103 | 13 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[modality].local:modality:sequencing | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |