Omics · study · 2026
Transcriptome analysis of breast tumour tissue and adjacent normal
Listed in NCBI GEO
Patients with cancer that respond to immunotherapy benefit from prolonged and possibly indefinite progression free survival.
Description
Response rates vary across cancer types, with solid carcinomas generally being the poorest responders at between 10-20 %. Understanding the differences between responders (the 10- 20%) and non-responders (the 80-90%) could identify ways to improve response rates.
In this project we investigate transcriptome changes in breast cancer tissue which may help understanding the differences in treatment responses.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE318nnn/GSE318780 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE318780 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1420535 ncbi.nlm.nih.gov/bioproject/PRJNA1420535 ↗
project · from NCBI GEO
- PubMed 42303597 pubmed.ncbi.nlm.nih.gov/42303597 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Homo sapiens
- From keywords
- Life Sciences
- Inferred from text
- Cancer 75%
Provenance · 1 source records, 8 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE318780 | 11 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[disease].local:disease:cancer | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |