Omics · dataset · 2026
Pancreatic adenocarcinoma treated with MEK, autophagy and immune checkpoint inhibitors reveals a responsive epithelial subtype within the heterogenous tumor that is enriched in murine models but not in humans
Listed in Teesside University Research Data Repository
Single-Nucleus RNA-Seq Data from Pancreatic Cancer patients on clinical trial.
Description
Includes integrated gene expression seurat object with raw counts and scaled data as well as metadata annotations for each cell. Also includes integrated VIPER inferred protein activity object with metadata labels, and R script with code for survival analyses, frequency plots, and GSEA enrichment analyses.
See manuscript methods for further detail.
Links
Where it is published
- DOI doi.org/10.17632/52hc7f6shv.1 ↗
DOI / persistent id · from researchdata tees ac uk
Catalogue records · 1
- OAI-PMH record data.mendeley.com/oai?verb=GetRecord&metadataPrefix=oai_dc&identifier=oai%3Adata… ↗
metadata API · from researchdata tees ac uk
Topics
- From keywords
- Earth & Environmental Science · Life Sciences · Medicine & Health · Single-cell RNA sequencing
- Inferred from text
- Cancer 75% · RNA sequencing 65%
Provenance · 1 source records, 11 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| Teesside University Research Data Repository | oai:data.mendeley.com/52hc7f6shv.1 | 14 h ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| concepts[disease].local:disease:cancer | enrichment · researchdata tees ac uk | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[field].local:field:earth-environmental | mapping · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| concepts[field].local:field:medicine-health | mapping · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| concepts[modality].local:modality:rna-seq | enrichment · researchdata tees ac uk | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[modality].local:modality:single-cell-rna-seq | mapping · researchdata tees ac uk | vocabulary-mapper@1.0.0 | keywords['Single-Cell RNA Sequencing'] |
| description | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | /metadata/dc/description |
| license | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | /metadata/dc/rights |
| publication_date | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| title | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | /metadata/dc/title |