Omics · study · 2026
EV Modulates Osteogenic differentiation in hPDL-MSCs
Listed in NCBI GEO
Periodontal homeostasis is maintained by a delicate balance between tissue regeneration and degradation, orchestrated through complex regulatory networks of cellular and molecular signaling.
Description
The delivery of microRNAs (miRNAs) by EVs serves as a crucial post-transcriptional regulatory mechanism, fine-tuning these signaling cascades. In this study, we identified significant candidates contained in the EVs secreted by human periodontal ligament mesenchymal stem cells (hPDL-MSCs) that contribute to PDL-MSC homeostasis and osteogenic differentiation.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE312nnn/GSE312257 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE312257 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1372738 ncbi.nlm.nih.gov/bioproject/PRJNA1372738 ↗
project · from NCBI GEO
- PubMed 42230452 pubmed.ncbi.nlm.nih.gov/42230452 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Homo sapiens · Non-coding RNA profiling by array
- From keywords
- Life Sciences
Provenance · 1 source records, 7 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE312257 | 10 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:non-coding-rna-profiling-by-array | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |