Table · dataset · 2026
Table 2_NDM-Producing Escherichia coli subdural empyema mimicking chronic subdural hematoma: a case report.docx
Listed in figshare and Loughborough Research Repository — shown once because both records carry DOI 10.3389/fmed.2026.1930920.s002
Background<p>Subdural empyema is a life-threatening intracranial infection that may mimic chronic subdural hematoma on non-contrast computed tomography (CT), delaying diagnosis and source control.
Description
Intracranial infection caused by New Delhi metallo-β-lactamase (NDM)-producing Escherichia coli is rare and may be overlooked when bloodstream infection appears microbiologically controlled.</p>Case presentation<p>An 82-year-old man presented with fever and progressive neurological deterioration.
Chest computed tomography (CT) suggested right lower lobe pneumonia, whereas serial head CT scans showed a left frontotemporoparietal subdural collection that was repeatedly interpreted as chronic subdural hematoma. Blood culture yielded multidrug-resistant Escherichia coli, and blood metagenomic next-generation sequencing (mNGS) detected E. coli together with blaNDM and other resistance determinants. Despite microbiologically guided antimicrobial therapy and subsequent clearance of blood cultures, fever, impaired consciousness, and enlargement of the subdural lesion persisted.
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Burr-hole exploration on March 22 revealed yellow purulent material rather than hematoma, establishing the anatomical diagnosis of subdural empyema and providing source control. Conventional culture of the surgically obtained subdural pus also yielded multidrug-resistant E. coli, while pus mNGS detected E. coli, blaNDM, blaCTX-M, and mcr-1. At the latest follow-up, the patient was undergoing further rehabilitation at a rehabilitation hospital.
His vital signs were stable, and his Glasgow Coma Scale score was 15.</p>Conclusion<p>Negative follow-up blood cultures do not exclude persistent compartmentalized intracranial infection. In bacteremic patients with neurological deterioration and an enlarging subdural collection, subdural empyema should be reconsidered and timely source control should not be delayed.</p>
Links
Where it is published
- DOI doi.org/10.3389/fmed.2026.1930920.s002 ↗
DOI / persistent id · from figshare com
Catalogue records · 1
- OAI-PMH record api.figshare.com/v2/oai?verb=GetRecord&metadataPrefix=oai_dc&identifier=oai%3Af… ↗
metadata API · from figshare com
Topics
- From keywords
- Astronomy & Astrophysics · Chemistry · Chemistry · Computer Science & AI · Computer Science & AI · Earth & Environmental Science · Earth & Environmental Science · Economics & Finance · Economics & Finance · Engineering · Engineering · Foetal development and medicine · Foetal development and medicine · Humanities · Humanities · Life Sciences · Life Sciences · Materials Science · Mathematics & Statistics · Medicine & Health · Medicine & Health · Ocean & Atmospheric Science · Psychology & Behavioral Science · Social Science · Social Science
- Inferred from text
- Computed tomography 75% · Sequencing 75% · Tabular 65%
Provenance · 2 source records, 33 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| figshare | oai:figshare.com:article/33970399 | 8 d ago | JSON v1 |
| Loughborough Research Repository | oai:figshare.com:article/33970399 | 7 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].anzsrc:field:321501 | mapping · figshare com | vocabulary-mapper@1.0.0 | keywords['Foetal Development and Medicine'] |
| concepts[field].anzsrc:field:321501 | mapping · repository lboro ac uk | vocabulary-mapper@1.0.0 | keywords['Foetal Development and Medicine'] |
| concepts[field].local:field:astronomy | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:chemistry | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:chemistry | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:computer-science-ai | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:computer-science-ai | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:earth-environmental | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:earth-environmental | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:economics-finance | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:economics-finance | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:engineering | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:engineering | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:humanities | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:humanities | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:materials-science | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:mathematics-statistics | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:medicine-health | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:medicine-health | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:ocean-atmospheric | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:psychology-behavioral | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:social-science | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:social-science | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[modality].local:modality:ct | enrichment · figshare com | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[modality].local:modality:sequencing | enrichment · figshare com | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[modality].local:modality:tabular | enrichment · figshare com | keyword-concept-rules@1.0.0 | title+description (65%) |
| description | source · figshare com | connector:figshare_com@1.0.0 | /metadata/dc/description |
| license | source · figshare com | connector:figshare_com@1.0.0 | /metadata/dc/rights |
| publication_date | source · figshare com | connector:figshare_com@1.0.0 | |
| title | source · figshare com | connector:figshare_com@1.0.0 | /metadata/dc/title |