Omics · study · 2026
Effect of BMP2, BMP3, BMP4, IL6, LIF, and OSM on the gene expression profiles of two patient-derived glioblastoma neurosphere lines.
Listed in NCBI GEO
To identify microenvironmental influences on glioblastoma (GBM) cell death response, a secreted factor modulatory screen was conducted on primary patient-derived GBM neurospheres.
Description
This screen identified several protein ligands that broadly altered GBM cell death response. To gain a better understanding of the mechanisms by which they alter cell death, we performed RNA-seq on the neurospheres following exogenous addition of the protein ligands.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE312nnn/GSE312023 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE312023 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1372077 ncbi.nlm.nih.gov/bioproject/PRJNA1372077 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Homo sapiens
- From keywords
- Life Sciences
- Inferred from text
- RNA sequencing 65%
Provenance · 1 source records, 8 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE312023 | 11 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |